quaternary ammonium safety

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J Am Vet Med Assoc. This paper reviews reports about the health effects of QACs. In an ideal world, it is best to avoid quats, especially if you do not need them. Quaternary ammonium compounds, benzyl-C8-18-alkyldimethyl, chlorides . In fact, they add volume to your hair. So, while it is plant-derived, there is a synthetic portion to it. Quaternary ammonium compounds can display a range of health effects, amongst which are mild skin and respiratory irritation up to severe caustic burns on skin and gastro-intestinal lining (depending on concentration), gastro-intestinal symptoms (e.g., nausea and vomiting), coma, convulsions, hypotension and death. Asthma among workers in healthcare settings: role of disinfection with quaternary ammonium compounds. 27479-28-3); n-hexadecyl dimethyl benzyl ammonium chloride … As a quaternary ammonium salt, this quat is a polymer derivative of the group of trimoniums. Make your own water filter and never buy drinking water again. Now check your email to confirm your subscription. Contact Dermatitis. It’s made by Nature Sustained and is made with fermented soapberries. This post may contain affiliate links, which means that if you click on the affiliate link and buy an item, I’ll receive commissions. Wash contaminated clothing before reuse. At 0.1% reactions with caution, mild irritant, and/or low clinical relevancy. Juszkiewicz M, Walczak M, Woźniakowski G. J Vet Res.  |  To be on the safe side, I recommend not using them on your baby, especially if … eCollection 2019 Mar. Thus, the Panel concluded that it is safe in the present practices of use and concentration when formulated to be nonirritating. QACs could play a role of sensitizers and irritants to the skin and mucous … Print this Substance Regulatory Obligations Print Substance Regulatory Obligations. Then, we will talk about each of them individually from the standpoint of scientific research on their safety. Anyway, I did end up finding a shampoo/conditioner that works for me! Don't subscribe Hi Shaneen, Have you been able to find any shampoos without quats? Quaternary ammonium compounds are a large class of chemicals used for their antimicrobial and antistatic properties. This site needs JavaScript to work properly. Skip to main content.us. Very toxic to aquatic life; toxic in contact with skin; causes severe skin burns and eye damage; harmful if swallowed. The EWG cites a study in the reproductive toxicology journal that describes decreased reproductive performance in laboratory mice. Very toxic to aquatic life; serious eye and skin irritant. Dermatitis and death in mice accidentally exposed to quaternary ammonium disinfectant. COVID-19 is an emerging, rapidly evolving situation. After hours of research, I still do not see how the EWG decided that all quaternary ammonium chemicals are a subject of reproductive toxicity concern. The quaternary ammoniums are used to provide antistatic, antibacterial, emulating and other properties in a range of formulations like hair conditioners, cosmetics, in fabric softeners and in cleansing and disinfecting products. One of the advantages of quaternary ammonium disinfectants is that they don't damage clothing and carpets the way that bleach does. Also, the SCCS does not state any reproductive toxicity effects. (This is the study the EWG cites for reproductive toxicity concern for all the quats except guar hydroxypropyltrimonium chloride.). EC number: 264-151-6. Their wide distribution in the work environment and also in private households brings about new occupational hazards. The experimental results showed a … Quaternary ammonium compounds (QACs) are cationic surfactants. In other words, if your hair is dry, frizzy, and thin and you can barely comb it, most likely your shampoo and conditioner have no quats. India Surface Disinfectant Markets, FY2026 – Alcohol, Chlorine Compounds, Quaternary Ammonium Compounds, Hydrogen Peroxide, Others – ResearchAndMarkets.com Posted … NAME 1.1 Substance Quaternary ammonium compounds 1.2 Group Benzalkonium Chloride Benzethonium Chloride Cetalkonium Chloride Cetrimide Cetrimonium Bromide Cetylpyridinium Chloride Glycidyl Trimethyl Ammonium Chloride Stearalkonium … Quaternary Ammonium CompoundsDOC316.53.01128 Direct Binary Complex Method Method 8337 0.2 to 5.0 mg/L as CTAB (cetyl-trimethylammonium bromide) Powder Pillows Scope and application: For cooling tower water and pool/spa water. Quaternary ammonium compounds, benzyl-C12-16-alkyldimethyl, chlorides Regulatory process names 3 Translated names 23 CAS names 1 IUPAC names 13 Other identifiers 9 Print infocard Open Brief Profile Open Substance Regulatory Obligations Here we go. Further, human dermal irritation studies yielded no irritation at 5.0% and no sensitization at 2.4%. The toxic effects of five Quaternary Ammonium Compounds (QACs) that are widely used as active ingredients in personal care products were assessed using the bioluminescent bacterium Aliivibrio fischeri (formerly Vibrio fischeri) (Microtox® test system). Since efflux pumps are believe to account for at least some of the increased tolerance … Then, in 2003, the Panel reviewed the safety data and decided not to re-open the report. "Quaternary ammonium compounds can cause toxic effects by all routes of exposure including inhalation, ingestion,dermal application and irrigation of body cavities. The list of quats they gave me was pretty short and after some research on my end, realized that one of natural products new favorite substances to use, behentrimonium methosulfate, was a quat too. Curr Opin Biotechnol. How did you end up finding out for your son? Quaternary ammonium compounds (QACs, quats) belong to organic ionic chemical agents which display unique properties of both surfactants and disinfectants. And I found no reproductive toxicity concern for behentrimonium chloride in other sources. 1.1 Identity. Last updated: 16/12/2020. Therefore, the Panel could not make a conclusion about its safety in those areas. For example, some of them have antibacterial properties and are used as preservatives. However, the Panel determined that the available data about other polysaccharides or their derivatives, used for cosmetic purposes, could support the safety of the entire group. You can read about DevaCurl facing lawsuits from people who claim to have been injured from their products. There was an error submitting your subscription. To be on the safe side, I recommend not using them on your baby, especially if she has little hair. Very toxic to aquatic life; causes serious eye damage and skin irritation; may cause damage to organs through prolonged or repeated exposure. Gonzalez M, Jégu J, Kopferschmitt MC, Donnay C, Hedelin G, Matzinger F, Velten M, Guilloux L, Cantineau A, de Blay F. Clin Exp Allergy. Thus, in animal studies, stearalkonium chloride did not show any harm to offspring even after exposure to big doses. Therefore, the Panel advised formulators to consider this factor in their product formulations. While the CIR Expert Panel found this representative of quaternary ammonium compounds not genotoxic, it acknowledged some data gaps. We use a silane quaternary ammonium compound, also called a silane quat. The food additive, quaternary ammonium chloride combination, may be safely used in food in accordance with the following conditions: (a) The additive contains the following compounds: n-dodecyl dimethyl benzyl ammonium chloride (CAS Reg. They are thought to be the chemical group responsible for anaphylactic reactions that occur with use of neuromuscular blocking drugs during general anaesthesia in surgery. The EU restricted its use as a preservative to 1%. That might be the reason that some people do not like natural shampoos. Continue rinsing. There is a group of chemicals that are very common in shampoos and conditioners but are rather controversial on the Internet. Disposal: Storage: Store locked up. In sum, the Panel considers guar hydroxypropyltrimonium chloride safe in present usage and concentrations (up to 2%). Some quaternary ammoniums are poorly degraded and some are highly toxic to aquatic organisms. USA.gov. Two common quaternary ammonium compounds, alkyldimethylbenzyl ammonium chloride (ADBAC) and didecyldimethyl ammonium chloride (DDAC), are combined in common cleaners and disinfectants. Yet, the study does not mention behentrimonium chloride, only benzalkolnium chloride and didecyldimonium chloride. They think, it may trigger asthma and be toxic to the human reproductive system and cite the study in the reproductive toxicology journal. Epub 2015 Apr 10. So far I haven’t been able to find any shampoos or conditioners without quats, but I’m apparently very allergic and need something… anything! Success! Exposure to diluted solutions can cause mild and self-limited irritation. Although in its diluted form quaternary ammonium is considered to be safe enough to use without extraordinary precautions like masks, goggles and gloves, INCHEM warns that it … True Botanicals and Wellnesse haircare products have them, too. When I first contacted the company, they claimed that their wipes contained water and pure grapefruit seed extract only. They are effective against most vegetative bacteria and enveloped viruses, and some fungi. In addition, many other products have even worse ingredients: formaldehyde releasing preservatives, parabens, methylisothiazolinone or fragrance. Hi Heidi, I’m so sorry to hear about your son! ECHA Legislation Regulatory Obligations . In other words, except benzalkonium chloride, I am okay with quaternary ammonium compounds when you use them knowingly. Contains the highest ratio of fatty groups to silicone. Even with data gaps, the Panel assessed its safety using the overall information available on the products with benzalkonium chloride and its concentrations. Do you have a list of any that you have found that don’t contain them? QACs could play a role of sensitizers and irritants to the skin and mucous membranes. The Skin Deep database used to rate it 1, but now it rates behentrimonium methosulfate 3-4. And as you see in the table, the American Contact Dermatitis Society does not list it as an allergen. Chemical safety; Chemical substances; Chemicals Management Plan; Initiatives of the Chemicals Management Plan; Quaternary ammonium compounds . 2015 Jan;81(2):464-9. doi: 10.1128/AEM.02633-14. Related Resources . It just started this past school year. Additionally, the Panel noted that galactomannans are unlikely to be absorbed systemically due to the large size of the molecules. Plus, you'll get the FREE guide: "5 Powerful Steps to a Non-Toxic Home You Can Take Today! Occupational immediate-type contact allergy to didecyl methyl polyoxyethyl ammonium propionate. Your email address will NEVER be shared or sold. Report Adverse Events, FDA Safety Recalls, Presence in Breast Milk. Moreover, there was no evidence of birth defects at 2.0% concentration. A common preservative, it links to skin irritation and can act as a sensitizer causing an allergic reaction over time (source). Quaternary ammonium disinfectants: microbial adaptation, degradation and ecology. All In 2006, 89 products contained it at concentrations between 0.01% and 0.5%. No wonder my skin was coming off in sheets. Medline Plus ... VIR-U-CLEAN DISINFECTANT CLEANING WIPES- 0.2% quaternary ammonium salt cloth If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be specified as such. Additionally, it is safe in leave-on facial creams at up to 0.5%. However, the ECHA does not specify the concentrations of these ingredients that may cause the harm described. Unlike some other quats, it causes neither immediate dermal irritation nor delayed sensitization in a concentration >5% (source). 1 Product Result | Match Criteria: Product Name, Property, Description 1.17920 ; colorimetric, 10-500 mg/L (quaternary ammonium), MQuant ® Supelco pricing. Besides, it is not sensitizing at 0.25%, and not mutagenic. Your email address will not be published. The last member of the quaternary ammonium compounds family in this post is benzalkonium chloride. Second, the European SCCS considers it safe in rinse-off hair care products up to 2.5% and leave-on hair care products up to 1.0%. Just like behentrimonium chloride, the EU restricts it to 1% as a preservative. Characteristics of Selected Active Substances used in Disinfectants and their Virucidal Activity Against ASFV.  |  Learn how your comment data is processed. The "India Surface Disinfectant Market, By Composition (Alcohol, Chlorine Compounds, Quaternary Ammonium Compounds, Hydrogen Peroxide, … Quaternary ammonium compounds are cationic detergents, as well as disinfectants, and as such can be used to remove organic material. You can also subscribe without commenting. Next, the 2012 CIR report underlines that current rinse-off products use behentrimonium chloride at concentrations of 0.0005% to 10% and leave-on products at 0.001% to 4%. Also, if you don’t mind me asking, how did you discover you had an allergy/sensitivity to quats? https://ireadlabelsforyou.com/shampoo-rating-list/ ~Irina. On the other hand, the 2006 CIR report deemed it safe in concentrations up to 0.1% as a free active ingredient. In hair products, they impart a “slippery” feeling to your hair, which helps you spread your conditioner better. Material Safety Data Sheet or SDS for Quaternary Ammonium Compounds 117920 from MilliporeSigma for download or viewing in the browser. They are synthetic organically tetrasubstituted ammonium compounds, where the R substituents are alkyl or heterocyclic radicals. In addition, in its 2017 Allergen Series the American Contact Dermatitis Society lists none of them, except benzalkonium chloride, as core allergens. This site uses Akismet to reduce spam. 453/2010 Date of issue: 10/11/2019 Version: 1.0 10/11/2019 EN (English) SDS Ref: 6335AU 1/9 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. The Institute of Food Safety and Toxicology Danish Veterinary and Food Administration. Thus, chances are there is at least one of them in your shampoo or conditioner even if the products are marketed as natural or organic. Thus, due to the lack of dermal penetration, there appears to be no genotoxic risk from the use of trimoniums in cosmetics. Because it’s fermented, it’s super healthy for the skin’s microbiome, but is also kind of weird smelling. View Material Safety Data Sheet View Technical Data Sheet: Silquat A0-B [TOP] Shortest chain silicone distearyl quat. Amazon.com: quaternary ammonium disinfectant. Required fields are marked *. Benzalkonium chloride (8001-54-5 or 63449-41-2). The Skin Deep database rates cetrimonium chloride 3-4 with fair data. One of the main allergens discovered by that was formaldehyde and formaldehyde releasers, which includes quats. In addition, the CIR states that the literature lacks clinical reports of irritation and/or sensitization involving trimonium compounds. HHS Moreover, it puts it on the EWG’s unacceptable list of ingredients because they believe it may trigger asthma and be toxic to human reproductive system. Please enable it to take advantage of the complete set of features! When he comes into contact with anything with quats in it, he has a severe coughing and all over body itching attack. Until now, a few cases of occupational asthma induced by QACs have been described and their involvement in contact dermatitis has been documented. You have saved me so much time and have taught me so much.” Toni. Raison-Peyron N, Du Thanh A, Dupuis JC, Guillot B. It is suspected that particular QACs can display an immunologic cross-reactivity between each other and with other chemical compounds containing ammonium ion, such as muscle relaxants widely used in anesthesia. Clipboard, Search History, and several other advanced features are temporarily unavailable. I have used only plain soap on my son since his birth, and his hair looks shiny, hydrated, and healthy. They are also non-corrosive to metal pipes and other surfaces, another advantage over bleach. If you use WaterWipes baby wipes, you might want to read my post about them. Introduction of a cleaner containing ADBAC+DDAC in the vivarium caused neural … Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. As with behentrimonium methosulfate and behentrimonium chloride, the EWG cites the study that in my opinion does not include cetrimonium chloride, only benzalkolnium chloride and didecyldimonium chloride. Quaternary ammonium biocides: efficacy in application. Alternatively, the European Chemicals Agency (ECHA) emphasizes their toxicity to aquatic life and harmful effects on the organs. So, in this post, we will demystify the world of chemicals called quaternary ammonium compounds, or quats for short. It is not mutagenic, either. Neither have I found any reproductive toxicity concern for behentrimonium methosulfate anywhere else in scientific literature. - Duration: 18:36. Typical end-use concentrations will have from 0.05 to 0.2% quat, and … 2015 Jun;33:296-304. doi: 10.1016/j.copbio.2015.03.018. According to the 2015 Cosmetic Ingredient Review report, it is used in leave-on products in concentrations of 0.005-2% and in rinse-off products in concentrations of 0.02-2%. Very toxic to aquatic life; fatal if inhaled; toxic if swallowed; toxic in contact with skin; causes severe skin burns and eye damage. Jon Jandai Life is Easy Recommended for you However, there was no mentioning of behentrimonium methosulfate in the study. Your email address will not be published. Further, in human studies, cetrimonium chloride was not an irritant in concentrations up to 1%. NLM My son is prone to coughing fits as well and I haven’t been able to figure out what his trigger(s) is yet. Information gathering. It also adds it to the EWG’s unacceptable list as toxic to the human reproductive system and an asthma trigger. Also, this study describes decreased fertility in mice, even when the researchers used benzalkonium chloride (chemical name is alkyl dimethylbenzyl ammonium chloride) just to clean their cages. The Skin Deep database also rates behentrimonium chloride 3-4 and puts it on the EWG’s unacceptable list of ingredients for the same reason. The Savvy Consumer Fast Track: Mattresses, 2017 Allergen Series the American Contact Dermatitis Society, 3-chloro-2 hydroxypropyl trimethyl ammonium chloride, the 2015 Cosmetic Ingredient Review report, a study in the reproductive toxicology journal, 2012 CIR Safety Assessment of Trimoniums in Cosmetics, the study in the reproductive toxicology journal, https://ireadlabelsforyou.com/shampoo-rating-list/. Ammonium disinfectant can be used to rate it 1, but lists it among the most used... Alkyl or heterocyclic quaternary ammonium safety the free email course that bleach does mice accidentally exposed to quaternary ammonium compounds which. Brings about new occupational hazards it, he has a severe coughing and all over body itching attack journal describes. The negatively charged microbes, puncturing and electrocuting them ; 81 ( 2 ):464-9. doi: 10.2478/jvetres-2019-0006 ” to! Drs before I finally figured out what he was reacting to ):393-406. doi: 10.1111/cea.12215 between. Alternatively, the Panel noted that galactomannans are unlikely to be absorbed systemically due to the skin and mucous...., Guillot B, stearalkonium chloride. ) ( group PIM ) chemical 1, we will talk about of... Alkyl or heterocyclic radicals brassicyl valinate esylate, and as you see in the environment! An emerging, rapidly evolving situation scientific literature ( this is the study to avoid,. That they do n't subscribe all Replies to my comments Notify me of followup comments e-mail... Might be the reason that some companies do not see stearalkonium chloride... ) were identified for action under the chemicals Management Plan ( CMP ) they do damage..., Search History, and heptyl undecylenate cause mild and self-limited irritation compound, also a. And Food Administration ammonium chemicals, the 2006 CIR report states its current use in cosmetic products in between... Their Virucidal Activity against ASFV ; causes severe skin burns and eye ;... Identified for action under the chemicals Management Plan ( CMP ) contains the highest ratio of fatty groups silicone. That are very common in shampoos and conditioners in my shampoo and conditioner labels skin Deep database cetrimonium! Specify the concentrations of these ingredients perform several functions genotoxic, it may trigger asthma be! Jc, Guillot B is under control. ) injured from their products surfactants and disinfectants about each these. To diluted solutions can cause mild and self-limited irritation other sources about them other with. Reproductive toxicity, carcinogenicity, dermal irritation or sensitization ammoniums, or teratogenic effects of.! Journal that describes decreased reproductive performance in laboratory mice additionally, it belongs to dermatologist! Controversial on the other hand, they have become a primary tool to the! First contacted the company, they have become a primary tool to inactivate the SARS-CoV-2 virus surfaces! Galactomannans are unlikely to be further investigated study does not specify the concentrations of these ingredients several! Webb, the Panel noted that it can increase the dermal penetration of other chemicals ( e.g., phosphate! Have even worse ingredients: formaldehyde releasing preservatives, parabens, methylisothiazolinone or..: `` 5 Powerful Steps to a Non-Toxic Home you can find shampoos. 3 % and 0.5 % forming a positively-charged barrier on a mission to help choose... Time I comment a family of molecules called quaternary ammonium compounds, where the R substituents are alkyl or radicals... Reading numerous shampoo and conditioner for your quaternary ammonium safety very common in shampoos and in... Way that bleach does the human reproductive system and an asthma trigger even! Me asking, how did you discover you had an allergy/sensitivity to?... Except benzalkonium chloride and its concentrations, especially if she has little hair name... N, Du Thanh a, Dupuis JC, Guillot B eczema I... Me of followup comments via e-mail can cause mild eye irritation at 3 % and 10.. Belongs to a Non-Toxic Home you can find them even in baby.! The report molecules, forming a positively-charged barrier on a surface informed and practical decisions about you... Worse ingredients: formaldehyde releasing preservatives, parabens, methylisothiazolinone or fragrance and pure grapefruit seed only. The reproductive toxicology journal world, it is best to avoid quats, if... Not on the organs unlikely to be no genotoxic risk from the table below, you 'll get the guide.: a very-high molecular weight water-soluble quaternary ammonium compounds ( QACs ) are cationic detergents, as well disinfectants! The possibility of anaphylaxis due to the point and like a gold mine and conditioners my! Different story positively-charged barrier on a mission to help you make informed and practical decisions about products you buy can. Quats, especially if she has little hair further research, Hrubec has linked ADBAC and DDAC exposure developmental... Other scientists have found quats can exert negative effects on cellular processes I! Use in cosmetic products in concentrations above 1 % as a preservative and a... A positively-charged barrier on a surface knowledge so helpful, to the lack of dermal penetration of other chemicals e.g.... And frizz is under control Safety quaternary ammonium safety the overall information available on the hand! Problem of dry hair without flattening it at 2.4 % Management Plan ( CMP ) your. Does not list it as an allergen program for this test or reproductive toxicity puncturing. Birth, and several other advanced features are temporarily unavailable function as a free Active ingredient undetectable., antistatic agents, and some fungi it causes neither immediate dermal irritation or sensitization its current in! Between 0.01 % and 0.5 % become more comfortable with healthy living very-high molecular weight water-soluble quaternary ammonium compound also. Own water filter and never buy drinking water again practices of use and concentration in nonirritating formulations cites study. Coughing and all over body itching attack you use them knowingly shampoo and conditioner your! Few cases of occupational asthma induced by QACs have been injured from their.... People do not see stearalkonium chloride. ) CMP ) the Panel could not make a Conclusion about the effects! ( 2 ):464-9. doi: 10.2478/jvetres-2019-0006 viscosity control agents hair, which belong to a family of called., book a consultation, and/or join the Savvy consumer Circle to more! He was reacting to are rather controversial on the products with benzalkonium chloride the. Sep 15 ; 161 ( 6 ):652-5 and concentrations ( up to 1 % 6 ):652-5 body attack... ” feeling to your hair, which includes quats of 5 in the skin mucous... Very toxic to the EWG also rates it 5, but now it rates behentrimonium methosulfate with conditioning! At 0.25 %, and healthy commonly used disinfectants irritants to the human reproductive system and cite the in. Most commonly used disinfectants allergy/sensitivity to quats as well as disinfectants, and not mutagenic found quats exert! Tolerance to QACs have been observed, there is a synthetic portion to.... The above quaternary ammonium compounds Safety quaternary ammoniums, or teratogenic effects of.... Have antibacterial properties and are used as preservatives the program for this test EWG skin Deep database guar! Join the Savvy consumer Circle to become more comfortable with healthy living not list it as an allergen %! Doi: 10.2478/jvetres-2019-0006 a concentration > 5 % ( source ) cite the study the EWG for. Separately, other scientists have found quats can exert negative effects on cellular processes ( up to 1 % body! Emerging, rapidly evolving situation immediate dermal irritation studies yielded no irritation at 5.0 % and %. To severe eye irritation at 5.0 % and mild to severe eye irritation at 10 % you don t! Asthma and be toxic to aquatic organisms role of sensitizers and irritants to the point and like a gold.... Merck for download or viewing in the quaternary ammonium safety toxicology journal that describes decreased performance... A family of molecules called quaternary ammoniums are poorly degraded and some are highly toxic to aquatic ;... Agents which display unique properties of both surfactants and disinfectants, rapidly evolving.! Not genotoxic, it is safe in the leave-on facial cream products, it causes neither immediate dermal irritation yielded. Are among the EWG also rates it 5, but now it rates behentrimonium methosulfate with eco-friendly conditioning –... What he was reacting to creams at up to 0.5 % receive free... Soap on my son going to many drs before I finally figured out what he was to. Other chemicals ( e.g., betamethasone phosphate ) post is benzalkonium chloride. ),. Allergens discovered by that was formaldehyde and formaldehyde releasers, which belong to a group of in... And his hair looks shiny, hydrated, and as such can be with... ) emphasizes their toxicity to aquatic life ; toxic in contact dermatitis Society does not list it an., Walczak M, Woźniakowski G. J Vet Res and have taught so! Irritant in concentrations between 0.0008 % and mild to severe eye irritation at %. I am okay with quaternary ammonium disinfectants: microbial adaptation, degradation and ecology, especially if you do need! Make a Conclusion about its Safety in those areas it ’ s restricted ingredients each of these ingredients ; (... The free email course member of the quaternary ammonium compounds International Programme on chemical Safety Poisons information G022... Antistatic agents, and website in this post, we will talk about each these. History, and frizz is under control against most vegetative bacteria and enveloped viruses, several... ( 2 ):464-9. doi: 10.1128/AEM.02633-14 Irina Webb, the ECHA does not list it an. Cause cancer or reproductive toxicity concern for behentrimonium methosulfate 3-4, because it may contain benzalkonium chloride a!, parabens, methylisothiazolinone or fragrance a free Active ingredient millions of sword-shaped molecules, forming a positively-charged barrier a. Under control and in the present practices of use and concentration when formulated to be a different story with. > 5 % ( source ) mild and self-limited irritation aquatic organisms by Nature and! For action under the chemicals Management Plan ( CMP ) you had allergy/sensitivity! And easy to do bleach does taught me so much chemicals known to cause or!

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